Audeze LCD-3

[hyooga]

I am wondering which one can drive the LCD-3 better

MK VI+ or MK VIII SE?

[rockage]

The Little Dot MK VI+ will be the best option to drive the LCD-3 as it will have higher current output. The MK VIII SE is best for high impedance headphones that require large voltage swing.

[hyooga]

Is there a specific gain setting or I just have to test it out?

[rockage]

It's best to just test them out as it's largely personal preference.